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Cancer

Our commitment to cancer
In the fight against cancer, oncologists and patients are looking for improved treatments, more therapeutic options and commitment by drug companies to continual development. To meet these expectations, our scientists are working hard to develop innovative therapies for the treatment of certain types of cancer, as well as for chronic cancer pain and fatigue in chemotherapy cancer patients.

Early developments in the treatment of cancer

 
Research Our commitment to developing active treatments for cancer began in the 1960s. Alert Janssen researchers found that levamisole (an antiparasitic drug) was able to stimulate the immune system and help the body attack tumours and fight off infections. In 1989, a combined treatment with levamisole was officially recognized by the American Cancer Institute. Levamisole was the start of our commitment to oncology.
 
Recent developments in the treatment of cancer
Our current research is exploring new approaches to cancer treatment. Having gained new insights into the natural molecules that stimulate or suppress tumour growth, our researchers are developing innovative drugs to treat several of the most common human cancers and associated diseases. The mission of Janssen-Cilag's oncology programme is embraced in the slogan 'The Art of Living'. This emphasises the optimism that, with better treatments, patients with cancer will be able to regain control of their own life.

Chronic cancer pain
DUROGESIC™ is used for the management of chronic, intractable pain due to cancer. It is delivered by means of a special skin patch, which releases the active product (fentanyl) continuously into the body's circulation over a three-day period. The development of this drug has increased the number of treatment options available to patients requiring analgesia for continuous cancer pain.

Fatigue in cancer
The world's most successful therapeutic biotechnology product, EPREX (epoetin alfa) is used in the treatment of fatigue in cancer chemotherapy patients. EPREX increases the number of red blood cells gradually, thereby countering the fatigue and improving quality of life.

Hairy cell leukaemia (HCL)
Janssen-Cilag has a strong R&D commitment to haematology, resulting, among other things, in LEUSTATIN™ (cladribine), a new drug for hairy-cell leukaemia (HCL), developed by RWJPRI and the Scripps Research Institute. Before that, HCL was often fatal. In addition, because HCL affects only 3,000 patients worldwide, little was known about it.

Cladribine has now been available in several markets for several years. A single course of treatment is usually sufficient; encouraging results have also been seen in patients with other, more common types of haematological cancers and other diseases.

 
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